Outcomes of Type II Endoleak Treatment Using Ethylene Vinyl Alcohol Copolymer (OnyxTM)

Vasc Endovascular Surg. 2021 Jan;55(1):50-57. doi: 10.1177/1538574420964644. Epub 2020 Oct 12.

Abstract

Introduction: This study reports our experience with the use of an ethylene vinyl alcohol copolymer (Onyx™) for the treatment of type II endoleak after endovascular repair of abdominal aortic aneurysms (EVAR) in comparison to coils and cyanoacrylate glue.

Methods: Clinical data of all patients treated for type II endoleak following EVAR between 2009 and 2017 were retrospectively analyzed. Abdominal aortic aneurysm (AAA) diameter and AAA sac volume during follow-up were measured using computed tomography angiography (CTA). Treatment failure variables were created for the change in sac diameter and volume. An increase in sac diameter ≥ 5 mm was considered a failure, as was an increase ≥ 10% in AAA sac volume.

Results: 35 patients underwent treatment for a persistent type II endoleak following EVAR. Of these patients, 18 (51.4%) were treated with Onyx and 17 (48.6%) were treated with coils ± cyanoacrylate glue embolization. There were no significant differences between the 2 groups with regard to demographics. The average volume of Onyx used per treatment was 13.4 ml (range 4.5 ml- 39 ml). There was no difference in efficacy between the Onyx and non-Onyx group. Complications were limited to 1 non-target embolization without significant clinical sequelae.

Conclusions: Ethylene vinyl alcohol copolymer (Onyx™) embolization is similarly effective compared to traditional cyanoacrylate glue or coil embolization in the treatment of type II endoleak after EVAR.

Keywords: Onyx™; abdominal aortic aneurysm; embolization; endovascular; sac volume; type 2 endoleak.

Publication types

  • Comparative Study

MeSH terms

  • Aged
  • Aged, 80 and over
  • Aortic Aneurysm, Abdominal / surgery*
  • Blood Vessel Prosthesis Implantation / adverse effects*
  • Cyanoacrylates / administration & dosage*
  • Cyanoacrylates / adverse effects
  • Embolization, Therapeutic* / adverse effects
  • Embolization, Therapeutic* / instrumentation
  • Endoleak / diagnostic imaging
  • Endoleak / etiology
  • Endoleak / therapy*
  • Endovascular Procedures / adverse effects*
  • Female
  • Humans
  • Male
  • Polyvinyls / administration & dosage*
  • Polyvinyls / adverse effects
  • Retrospective Studies
  • Treatment Outcome

Substances

  • Cyanoacrylates
  • Polyvinyls
  • ethylene-vinyl alcohol copolymer