Updating the Free Radical Theory of Aging

Adam S Ziada; Marie-Soleil R Smith; Hélène C F Côté

doi:10.3389/fcell.2020.575645

Updating the Free Radical Theory of Aging

Front Cell Dev Biol. 2020 Sep 16:8:575645. doi: 10.3389/fcell.2020.575645. eCollection 2020.

Authors

Adam S Ziada^{1

2}, Marie-Soleil R Smith^{1

2}, Hélène C F Côté^{1

2

3}

Affiliations

¹ Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, BC, Canada.
² Centre for Blood Research, University of British Columbia, Vancouver, BC, Canada.
³ Women's Health Research Institute, Vancouver, BC, Canada.

No abstract available

Keywords: aging; clonal expansion; free radical theory of aging; mtDNA; mtDNA mutations; mtDNA replication; oxidative stress; polymerase gamma (POLG).