Investigating Cervical Risk Factors that Lead to Cytological and Biopsy Examination

Abstract

Introduction: Cervical cancer ranks the fourth prevalent cancer in women at the global level, and the second in poor countries. The main objectives of the present study were to investigate the risk factors associated with cervical cancer and to study their possible association with the decision to take a cervical biopsy.

Aim: The main objectives of this study were to investigate the risk factors associated with cervical cancer and to study their possible association with the decision to take a cervical biopsy.

Methods: It was cross-sectional study and we analyzed an online data posted on Kaggle. This Dataset is obtained from UCI Repository. A list of risk factors for cervical cancer leading to biopsy examination was included, such as age, number of sexual partners, first sexual intercourse, number of pregnancies, smoking variables, hormonal contraceptives, IUD, and sexually transmitted disease variables, Hinselmann, Schiller, Cytology, and Biopsy. The dataset was prepared for appropriateness through filtering invalid cases with missing data.

Results: The results of the study showed that the following variables were significantly associated with cytological examination: STD-Condylomotosis (p=0.035), STD-Pericondylomotosis (p=0.029), STD_HIV (p=0.006), Hinselmann (p<0.001), Schiller (p<0.001), and biopsy (p<0.001). the results also showed that the following variables were significantly associated with cytological examination.

Conclusion: Taken together, cytological variables or biopsy examination variables if carried out at an early stage, lead to better diagnostic and therapeutic options.

Keywords: HPV; Kaggle; cervical cancer; dataset; risk factors; sexually transmitted disease.