Presence of the aldehyde dehydrogenase 2 variant ALDH2*2 considerably increases EC50 of nitroglycerin

Presence of the aldehyde dehydrogenase 2 variant ALDH2*2 considerably increases EC₅₀ of nitroglycerin

Eur J Clin Pharmacol. 2021 Mar;77(3):431-433. doi: 10.1007/s00228-020-02999-6. Epub 2020 Oct 10.

Kentaro Ushijima^{1

2}, Chika Ogami³, Yasuhiro Tsuji⁴, Tatsuya Nagano^{5

6}, Akio Fujimura⁵

¹ Division of Clinical Pharmacology, Department of Pharmacology, Jichi Medical University, Tochigi, 329-0498, Japan. ushijima-kentarou@umin.ac.jp.
² Division of Pharmaceutics, Faculty of Pharmaceutical Sciences, Sanyo-Onoda City University, Yamaguchi, Japan. ushijima-kentarou@umin.ac.jp.
³ Department of Medical Pharmaceutics, Faculty of Pharmacy and Pharmaceutical Sciences, University of Toyama, Toyama, Japan.
⁴ School of Pharmacy, Nihon University, Chiba, Japan.
⁵ Division of Clinical Pharmacology, Department of Pharmacology, Jichi Medical University, Tochigi, 329-0498, Japan.
⁶ Department of Anesthesiology and Critical Care Medicine, Jichi Medical University, Tochigi, Japan.

No abstract available