Antimicrobial susceptibility pattern of Methicillin-resistant Staphylococcus Aureus isolates in Fauji Foundation Hospital Rawalpindi

J Pak Med Assoc. 2020 Sep;70(9):1633-1635. doi: 10.5455/JPMA.41422.

Abstract

The current study was conducted in the Department of Microbiology, Fauji Foundation Hospital, Rawalpindi, from July 2018 to January 2019. The main purpose of the study was to evaluate Methicillin-resistant Staphylococcus aureus antimicrobial susceptibility pattern. Clinical samples were collected and cultured according to Clinical and Laboratory Standards Institute (CLSI) guidelines. A total of 90(30%) samples were found to be methicillin-resistant out of 300 samples of Staphylococcus aureus. Major isolates were 42 (46.67%) from pus and 22 (24.44%) from tracheal tubes. The incidence ratio of Methicillin-resistant Staphylococcus aureus was high in the samples isolated from 69 (76.67%) females compared to those of 21 (23.33%) males. Patients were more in the age group of 41 to 60 years. Vancomycin 90 (100%) was sensitive to all strains followed by Chloramphenicol 66 (73.33%) and Doxycycline 52 (57.78%). Imipenem, Meropenem andAugmentin showed resistance to all strains.

Keywords: Methicillin-resistant Staphylococcus aureus, MRSA, Vancomycin, Antimicrobial susceptibility.

MeSH terms

  • Adult
  • Anti-Bacterial Agents / pharmacology
  • Anti-Bacterial Agents / therapeutic use
  • Female
  • Hospitals
  • Humans
  • Male
  • Methicillin-Resistant Staphylococcus aureus*
  • Microbial Sensitivity Tests
  • Middle Aged
  • Staphylococcal Infections* / drug therapy
  • Staphylococcal Infections* / epidemiology

Substances

  • Anti-Bacterial Agents