Severe COVID-19 initially presenting as mesenteric adenopathy

Pediatr Radiol. 2021 Jan;51(1):140-143. doi: 10.1007/s00247-020-04789-9. Epub 2020 Oct 10.

Abstract

Coronavirus disease 2019 (COVID-19) can present with abdominal pain in children and adults. Most imaging findings have been limited to characteristic lung findings, as well as one report of bowel-ischemia-related findings in adults. We report a case of COVID-19 in a healthy teenager who initially presented with isolated mesenteric adenopathy, typically a self-limited illness, which progressed to severe illness requiring intensive care before complete recovery. The boy tested negative for COVID-19 twice by polymerase chain reaction (PCR) from upper respiratory swabs before sputum PCR resulted positive. A high index of suspicion should be maintained for COVID-19 given the continued emergence of new manifestations of the disease.

Keywords: Abdomen; Adolescent; COVID-19; Computed tomography; Coronavirus; Lymph nodes; Mesentery; Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

Publication types

  • Case Reports

MeSH terms

  • Abdominal Pain / etiology
  • Adenosine Monophosphate / analogs & derivatives
  • Adenosine Monophosphate / therapeutic use
  • Adolescent
  • Alanine / analogs & derivatives
  • Alanine / therapeutic use
  • Antiviral Agents / therapeutic use
  • COVID-19 / complications
  • COVID-19 / diagnosis*
  • COVID-19 / therapy*
  • COVID-19 Testing / methods*
  • Diagnosis, Differential
  • Humans
  • Lymphadenopathy*
  • Male
  • Peritoneal Diseases*
  • Polymerase Chain Reaction / methods
  • Positive-Pressure Respiration / methods
  • Tomography, X-Ray Computed / methods
  • Treatment Outcome

Substances

  • Antiviral Agents
  • remdesivir
  • Adenosine Monophosphate
  • Alanine