Stent Thrombosis After Percutaneous Coronary Intervention: From Bare-Metal to the Last Generation of Drug-Eluting Stents

Alberto Polimeni; Sabato Sorrentino; Carmen Spaccarotella; Annalisa Mongiardo; Jolanda Sabatino; Salvatore De Rosa; Tommaso Gori; Ciro Indolfi

doi:10.1016/j.ccl.2020.07.008

Stent Thrombosis After Percutaneous Coronary Intervention: From Bare-Metal to the Last Generation of Drug-Eluting Stents

Cardiol Clin. 2020 Nov;38(4):639-647. doi: 10.1016/j.ccl.2020.07.008. Epub 2020 Sep 17.

Authors

Alberto Polimeni¹, Sabato Sorrentino¹, Carmen Spaccarotella¹, Annalisa Mongiardo², Jolanda Sabatino¹, Salvatore De Rosa¹, Tommaso Gori³, Ciro Indolfi⁴

Affiliations

¹ Division of Cardiology, Department of Medical and Surgical Sciences, "Magna Graecia" University, Viale Europa, Catanzaro 88100, Italy; Research Center for Cardiovascular Diseases, "Magna Graecia" University, Viale Europa, Catanzaro 88100, Italy.
² Division of Cardiology, Department of Medical and Surgical Sciences, "Magna Graecia" University, Viale Europa, Catanzaro 88100, Italy.
³ Kardiologie I, Zentrum für Kardiologie, University Medical Center Mainz, Deutsches Zentrum für Herz und Kreislauf Forschung, Langenbeckstraße 1, Standort Rhein-Main 55131, Germany.
⁴ Division of Cardiology, Department of Medical and Surgical Sciences, "Magna Graecia" University, Viale Europa, Catanzaro 88100, Italy; Research Center for Cardiovascular Diseases, "Magna Graecia" University, Viale Europa, Catanzaro 88100, Italy; Mediterranea Cardiocentro, Via Orazio, 2, Naples 80122, Italy. Electronic address: indolfi@unicz.it.

PMID: 33036724
DOI: 10.1016/j.ccl.2020.07.008

Abstract

Since their introduction in clinical practice in 1986, different types of coronary stents have been developed and become available for the treatment of coronary artery disease. Stent thrombosis (ST) is an uncommon but harmful complication after percutaneous coronary implantation, with a high occurrence of acute myocardial infarction and risk of mortality. Among several procedural and clinical predictors, the type of coronary stent is a strong determinant of ST. This article reviews the available evidence on the most used coronary stent types in the modern era and the related risk of ST.

Keywords: BMS; BRS; DES; Stent; Thrombosis.

Publication types

Review

MeSH terms

Absorbable Implants*
Drug-Eluting Stents*
Humans
Percutaneous Coronary Intervention
Polymers
Prosthesis Design
Stents* / adverse effects
Thrombosis / etiology*

Substances

Polymers