A unique type of fully covered metal stent for the management of post liver transplant biliary anastomotic strictures

BMC Gastroenterol. 2020 Oct 7;20(1):329. doi: 10.1186/s12876-020-01479-6.

Abstract

Background: We report our experience of treating anastomotic strictures using a novel type of fully covered metal stent (FCSEMS). This stent, known as the Kaffes Stent, is short-length with an antimigration waist and is easily removable due to long retrieval wires deployed within the duodenum.

Methods: Sixty-two patients underwent ERCP and Kaffes stent insertion for post-transplant anastomotic strictures following confirmation of a stricture on MRCP. These patients were retrospectively analysed for immediate and long-term stricture resolution, improvement in symptoms and liver function tests (LFTs), stricture recurrence and complication rates.

Results: Of the 56 patients who had their stent removed at the time of analysis, 54 (96%) had immediate stricture resolution and 42 continued to have long-term resolution (mean follow-up period was 548 days). Of the 16 patients with symptoms of biliary obstruction, 13 had resolution of their symptoms. Overall, there was a significant improvement in LFTs after stent removal compared to before stent insertion. Complication rates were 15% with only one patient requiring biliary reconstruction.

Conclusions: The Kaffes stent is effective and safe at resolving post liver transplant biliary anastomotic strictures.

Keywords: Anastomotic strictures; Biliary; ERCP; FCSEMS.

MeSH terms

  • Cholangiopancreatography, Endoscopic Retrograde / adverse effects
  • Constriction, Pathologic / etiology
  • Constriction, Pathologic / surgery
  • Humans
  • Liver Transplantation* / adverse effects
  • Retrospective Studies
  • Stents
  • Treatment Outcome