Cysteine-113 covalency inspires the development of Pin1 inhibitor

Signal Transduct Target Ther. 2020 Oct 6;5(1):225. doi: 10.1038/s41392-020-00339-9.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Cysteine* / chemistry
  • Cysteine* / metabolism
  • Enzyme Inhibitors / chemistry*
  • Humans
  • NIMA-Interacting Peptidylprolyl Isomerase* / antagonists & inhibitors
  • NIMA-Interacting Peptidylprolyl Isomerase* / chemistry
  • NIMA-Interacting Peptidylprolyl Isomerase* / metabolism

Substances

  • Enzyme Inhibitors
  • NIMA-Interacting Peptidylprolyl Isomerase
  • PIN1 protein, human
  • Cysteine