UV-LED disinfection of Coronavirus: Wavelength effect

Yoram Gerchman; Hadas Mamane; Nehemya Friedman; Michal Mandelboim

doi:10.1016/j.jphotobiol.2020.112044

UV-LED disinfection of Coronavirus: Wavelength effect

J Photochem Photobiol B. 2020 Nov:212:112044. doi: 10.1016/j.jphotobiol.2020.112044. Epub 2020 Sep 28.

Authors

Yoram Gerchman¹, Hadas Mamane², Nehemya Friedman³, Michal Mandelboim³

Affiliations

¹ Department of Biology and Environment, Faculty of Natural Science, University of Haifa and Oranim College, Tivon 3600600, Israel. Electronic address: gerchman@research.haifa.ac.il.
² School of Mechanical Engineering, Faculty of Engineering, Tel Aviv University, Tel Aviv 69978, Israel.
³ Central Virology Laboratory, Ministry of Health, Chaim Sheba Medical Center, Tel-Hashomer, Ramat-Gan, Israel; Department of Epidemiology and Preventive Medicine, School of Public Health, Tel-Aviv University, Israel.

Abstract

UV light-emitting diodes (UV LEDs) are an emerging technology and a UV source for pathogen inactivation, however low UV-LED wavelengths are costly and have low fluence rate. Our results suggest that the sensitivity of human Coronavirus (HCoV-OC43 used as SARS-CoV-2 surrogate) was wavelength dependent with 267 nm ~ 279 nm > 286 nm > 297 nm. Other viruses showed similar results, suggesting UV LED with peak emission at ~286 nm could serve as an effective tool in the fight against human Coronaviruses.

Keywords: COVID19; Corona; Coronavirus; SARS; UV-LEDs; Wavelength.

MeSH terms

Betacoronavirus / genetics
Betacoronavirus / isolation & purification
Betacoronavirus / radiation effects*
COVID-19
Coronavirus Infections / pathology
Coronavirus Infections / virology
Humans
Pandemics
Pneumonia, Viral / pathology
Pneumonia, Viral / virology
RNA, Viral / metabolism
Radiation Dosage
Real-Time Polymerase Chain Reaction
SARS-CoV-2
Ultraviolet Rays*
Virus Inactivation / radiation effects

Substances

RNA, Viral