First description of abdominal infection due to Alistipes onderdonkii

Anaerobe. 2020 Dec:66:102283. doi: 10.1016/j.anaerobe.2020.102283. Epub 2020 Oct 3.

Abstract

Alistipes spp is a genus of Gram-negative anaerobic rods involved in very few human diseases. We report the first case of abdominal infection due to Alistipes onderdonkii in a 58-year-old man with a history of chronic obstructive pulmonary disease. He presented with abdominal pain and general malaise after retrogastric drainage for a pancreatitis episode a few days earlier. After the diagnosis of diffuse peritonitis with perforation and necrotizing pancreatic collection, abundant pancreatic fluid was drained and yielded the isolation of A. onderdonkii in pure culture. Resistance to penicillin and moxifloxacin was documented for this strain. Treatment with metronidazole was prescribed, and the patient was discharged after improvement of his general condition.

Keywords: Alistipes onderedonkii; Anaerobes; Gene sequencing; MALDI TOF MS; abdominal Drainage.

Publication types

  • Case Reports

MeSH terms

  • Anaerobiosis
  • Anti-Bacterial Agents / therapeutic use
  • Bacteroidetes / classification*
  • Bacteroidetes / drug effects
  • Bacteroidetes / genetics
  • DNA, Bacterial
  • Humans
  • Intraabdominal Infections / diagnosis*
  • Intraabdominal Infections / drug therapy
  • Intraabdominal Infections / microbiology*
  • Male
  • Microbial Sensitivity Tests
  • Middle Aged
  • Peritonitis / diagnosis
  • Peritonitis / microbiology
  • RNA, Ribosomal, 16S
  • Treatment Outcome

Substances

  • Anti-Bacterial Agents
  • DNA, Bacterial
  • RNA, Ribosomal, 16S

Supplementary concepts

  • Alistipes onderdonkii