Synthesis and Characterization of Bidentate (P^N)Gold(III) Fluoride Complexes: Reactivity Platforms for Reductive Elimination Studies

Alexandre Genoux; Michał Biedrzycki; Estíbaliz Merino; Eva Rivera-Chao; Anthony Linden; Cristina Nevado

doi:10.1002/anie.202009359

Synthesis and Characterization of Bidentate (P^N)Gold(III) Fluoride Complexes: Reactivity Platforms for Reductive Elimination Studies

Angew Chem Int Ed Engl. 2021 Feb 19;60(8):4164-4168. doi: 10.1002/anie.202009359. Epub 2020 Dec 22.

Authors

Alexandre Genoux¹, Michał Biedrzycki¹, Estíbaliz Merino^{1

2}, Eva Rivera-Chao¹, Anthony Linden¹, Cristina Nevado¹

Affiliations

¹ Department of Chemistry, University of Zurich, Winterthurerstrasse 190, 8057, Zürich, Switzerland.
² Current address: Department of Organic and Inorganic Chemistry, Chemical Research Institute Andrés M. del Río (IQAR), University of Alcalá, 28805-Alcalá de Henares, Madrid, Spain.

PMID: 33015997
DOI: 10.1002/anie.202009359

Abstract

A new family of cationic, bidentate (P^N)gold(III) fluoride complexes has been prepared and a detailed characterization of the gold-fluoride bond has been carried out. Our results correlate with the observed reactivity of the fluoro ligand, which undergoes facile exchange with both cyano and acetylene nucleophiles. The resulting (P^N)arylgold(III)C(sp) complexes have enabled the first study of reductive elimination on (P^N)gold(III) systems, which demonstrated that C(sp² )-C(sp) bond formation occurs at higher rates than those reported for analogous phosphine-based monodentate systems.

Keywords: fluoride; gold(III); ligand exchange; reductive elimination.

Abstract

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