Exploring Graphene and MoS2 Chips Based Surface Plasmon Resonance Biosensors for Diagnostic Applications

Devi Taufiq Nurrohman; Ying-Hao Wang; Nan-Fu Chiu

doi:10.3389/fchem.2020.00728

Exploring Graphene and MoS₂ Chips Based Surface Plasmon Resonance Biosensors for Diagnostic Applications

Front Chem. 2020 Aug 26:8:728. doi: 10.3389/fchem.2020.00728. eCollection 2020.

Authors

Devi Taufiq Nurrohman^{1

2}, Ying-Hao Wang¹, Nan-Fu Chiu^{1

3}

Affiliations

¹ Laboratory of Nano-photonics and Biosensors, Institute of Electro-Optical Engineering, National Taiwan Normal University, Taipei, Taiwan.
² Department of Electronics Engineering, State Polytechnic of Cilacap, Cilacap, Indonesia.
³ Department of Life Science, National Taiwan Normal University, Taipei, Taiwan.

Abstract

Until now, two-dimensional (2D) nanomaterials have been widely studied and applied in the biosensor field. Some of the advantages offered by these 2D materials include large specific surface area, high conductivity, and easy surface modification. This review discusses the use of 2D material in surface plasmon resonance (SPR) biosensor for diagnostic applications. Two-dimensional material reviewed includes graphene and molybdenum disulfide (MoS₂). The discussion begins with a brief introduction to the general principles of the SPR biosensor. The discussion continues by explaining the properties and characteristics of each material and its effect on the performance of the SPR biosensor, in particular its sensitivity. This review concludes with some recent applications of graphene- and MoS₂-based SPR biosensor in diagnostic applications.

Keywords: 2D materials; MoS2; biosensor; diagnostic; graphene; surface plasmon resonance.

Publication types

Review