Whole-Genome Sequencing of Bacterial Isolates That Degrade the Cyanobacterial Toxin Microcystin-LR

Alexander T McCartney; Ji-Youn Yeo; Thomas M Blomquist; Jason F Huntley

doi:10.1128/MRA.00959-20

Whole-Genome Sequencing of Bacterial Isolates That Degrade the Cyanobacterial Toxin Microcystin-LR

Microbiol Resour Announc. 2020 Oct 1;9(40):e00959-20. doi: 10.1128/MRA.00959-20.

Authors

Alexander T McCartney¹, Ji-Youn Yeo², Thomas M Blomquist², Jason F Huntley³

Affiliations

¹ Bioinformatics Program, University of Toledo College of Medicine and Life Sciences, Toledo, Ohio, USA.
² Department of Pathology, University of Toledo College of Medicine and Life Sciences, Toledo, Ohio, USA.
³ Department of Medical Microbiology and Immunology, University of Toledo College of Medicine and Life Sciences, Toledo, Ohio, USA jason.huntley@utoledo.edu.

Abstract

We previously demonstrated that 13 bacterial isolates from Lake Erie, when grown in groups of four to five isolates per group, degraded the cyanobacterial toxin microcystin-LR (MC-LR) into nontoxic fragments. Whole-genome sequencing of these bacteria was performed to provide genus and species information and to predict putative MC-LR-degrading genes.