Nutritional Strategies in Prediabetes: A Scoping Review of Recent Evidence

Nutrients. 2020 Sep 29;12(10):2990. doi: 10.3390/nu12102990.

Abstract

Nutritional therapy has been conventionally recommended for people with prediabetes as a method to delay or halt progression to type 2 diabetes. However, recommended nutritional strategies evolve over time. Hence, we performed a scoping review on recently reported nutritional interventions for individuals with prediabetes. Ovid MEDLINE, PubMed, Embase, Scopus, CINAHL and PsycINFO databases were searched to identify relevant research articles published within the past 10 years. Ninety-five articles involving a total of 11,211 participants were included in this review. Nutritional strategies were broadly classified into four groups: low calorie diet, low glycemic index diet, specific foods, and a combination of diet and exercise. The most frequently assessed outcomes were plasma glucose, serum insulin, serum lipid profile, body mass index and body weight. More than 50% of reported interventions resulted in significant improvements in these parameters. Nutritional interventions have demonstrated feasibility and practicality as an effective option for prediabetes management. However, the intervention variability demonstrates the challenges of a 'one-size-fits-all' approach. Investigations in genetically diverse populations and objective assessment of progression rate to diabetes are necessary to better comprehend the impact of these nutritional strategies in prediabetes.

Keywords: diabetes mellitus; diet therapy; glucose intolerance; hyperglycemia; prediabetes; type 2.

Publication types

  • Review

MeSH terms

  • Blood Glucose / metabolism
  • Body Mass Index
  • Body Weight
  • Diabetes Mellitus, Type 2 / prevention & control*
  • Diet / methods*
  • Exercise / physiology*
  • Glycemic Index
  • Humans
  • Insulin / blood
  • Lipids / blood
  • Prediabetic State / blood
  • Prediabetic State / diet therapy*

Substances

  • Blood Glucose
  • Insulin
  • Lipids