Acquired Fanconi Syndrome in a Patient with Nontyphoidal Salmonella Bacteremia

Intern Med. 2021 Mar 1;60(5):761-764. doi: 10.2169/internalmedicine.5932-20. Epub 2020 Sep 30.

Abstract

Nontyphoidal Salmonella is a common cause of bacterial gastroenteritis, occasionally causing bacteremia. We herein report the case of an 80-year-old man who presented with bacteremia and pre-renal acute kidney injury (AKI) secondary to diarrhea caused by nontyphoidal Salmonella. Despite AKI improvement on fluid administration, some serological abnormalities, such as hypokalemia, hypophosphatemia, and hypouricemia, and abnormal urinary findings emerged, including renal glycosuria and aminoaciduria. Fractional excretion of phosphate and uric acid was increased, suggesting that the serological and urinary abnormalities may have arisen from Fanconi syndrome. Physicians should consider acquired Fanconi syndrome when patients with nontyphoidal Salmonella bacteremia present with electrolyte disorders.

Keywords: Fanconi syndrome; hypokalemia; hypophosphatemia; salmonella bacteremia.

Publication types

  • Case Reports

MeSH terms

  • Acidosis, Renal Tubular*
  • Aged, 80 and over
  • Bacteremia* / complications
  • Bacteremia* / diagnosis
  • Fanconi Syndrome* / complications
  • Fanconi Syndrome* / diagnosis
  • Humans
  • Hypophosphatemia*
  • Male
  • Salmonella