Many complex systems can be modeled as directed networks, which can be regarded as a generalization of undirected networks. In this paper, epidemic dynamics and immunization strategies in directed networks are studied. First, a Susceptible-Infected-Susceptible (SIS) model on a directed network is established employing the mean-field method, and its dynamics and epidemic threshold of the network are studied. Then based on the continuous degree technique, namely, considering the degree of a node as a continuous variable, we propose a method to calculate the epidemic threshold of the immunized network. Besides, some immunization strategies, including optimal immunization, random immunization, combined targeted immunization, and combined acquaintance immunization, and three special networks are considered. Finally, through numerical analysis, all immunization strategies are simulated and compared on different types of networks. We find that the nodes with the largest product of in-degree and out-degree are the most worthy of being immunized.
Keywords: combined acquaintance immunization; combined targeted immunization; directed network; optimal immunization; random immunization.