Association of a polymorphism in exon 3 of the IGF1R gene with growth, body size, slaughter and meat quality traits in Colored Polish Merino sheep

E Grochowska; D Lisiak; M Z Akram; O O Adeniyi; G Lühken; B Borys

doi:10.1016/j.meatsci.2020.108314

Association of a polymorphism in exon 3 of the IGF1R gene with growth, body size, slaughter and meat quality traits in Colored Polish Merino sheep

Meat Sci. 2021 Feb:172:108314. doi: 10.1016/j.meatsci.2020.108314. Epub 2020 Sep 18.

Authors

E Grochowska¹, D Lisiak², M Z Akram³, O O Adeniyi⁴, G Lühken⁴, B Borys⁵

Affiliations

¹ Department of Animal Biotechnology and Genetics, UTP University of Science and Technology, Mazowiecka 28 St, 85-084 Bydgoszcz, Poland. Electronic address: grochowska@utp.edu.pl.
² Department of Meat and Fat Technology, Prof. Wacław Dąbrowski Institute of Agricultural and Food Biotechnology, Rakowiecka 36 St., 02-532 Warsaw, Poland.
³ Department of Animal Production and Technologies, Niğde Ömer Halisdemir University, 51240 Niğde, Turkey.
⁴ Institute of Animal Breeding and Genetics, Justus-Liebig University, Ludwigstrasse 21, 35390 Giessen, Germany.
⁵ National Research Institute of Animal Production, Experimental Station Kołuda Wielka, Parkowa 1 St., 88-160 Janikowo, Poland.

PMID: 32987303
DOI: 10.1016/j.meatsci.2020.108314

Abstract

This study aimed to genotype the polymorphism (c.654G > A) in the exon 3 of the insulin-like growth factor 1 receptor gene (IGF1R) and to analyze its association with growth, body size, slaughter and meat quality traits in Colored Polish Merino sheep. In total, 67 traits were analyzed. The IGF1R polymorphism was genotyped using the polymerase chain reaction single-strand conformation polymorphism (PCR-SSCP) method. The MIXED procedure of the SAS software was used to assess the genotypic effects of the polymorphism (c.654G > A) on production traits of interest. The IGF1R c.654G > A genotypes were found to have a significant effect on the average daily gain between the 56th and 78th day of life, cold carcass, leg part, leg cut, fore shank, and kidney weights, as well as eye of loin depth, intramuscular fat content, and water-holding capacity of meat. The results suggest that the studied polymorphism may provide useful information for marker-assisted selection for increased meat performance in Colored Polish Merino sheep.

Keywords: Body size; Carcass; Growth; Insulin-like growth factor 1 receptor gene; Meat quality; Sheep; Trait.

MeSH terms

Animals
Body Size / genetics
Polymorphism, Single Nucleotide
Receptor, IGF Type 1 / genetics*
Red Meat / analysis*
Sheep, Domestic / genetics*
Sheep, Domestic / growth & development
Water

Substances

Water
Receptor, IGF Type 1