Encephalopathy and brain atrophy during induction chemotherapy in acute lymphoblastic leukemia

Qiao-Ru Li; Si-Mao Fu; Yin-Lei Mo; Yu Li; Cong Liang; Li-Na Wang; Wen-Yan Tang; Li-Bin Huang; Xue-Qun Luo; Yan-Lai Tang

doi:10.1002/ccr3.2969

Encephalopathy and brain atrophy during induction chemotherapy in acute lymphoblastic leukemia

Clin Case Rep. 2020 Aug 17;8(9):1858-1859. doi: 10.1002/ccr3.2969. eCollection 2020 Sep.

Authors

Qiao-Ru Li¹, Si-Mao Fu¹, Yin-Lei Mo², Yu Li², Cong Liang², Li-Na Wang², Wen-Yan Tang², Li-Bin Huang², Xue-Qun Luo², Yan-Lai Tang²

Affiliations

¹ Department of Pediatrics Zhongshan Hospital, Sun Yat-sen University Zhongshan China.
² Department of Pediatrics The First Affiliated Hospital, Sun Yat-sen University Guangzhou China.

Abstract

The MRI showed encephalopathy and brain atrophy of the left parietal lobe, occipital lobe and temporal lobe and decreased infiltration of the dura mater on T2-weighted imaging. But encephalopathy and brain atrophy could be improved with neurotrophic drugs and additional intelligence teaching.

Keywords: acute lymphoblastic leukemia; brain atrophy; chemotherapy; children; encephalopathy.