Inhibition in developmental disorders: A comparison of inhibition profiles between children with autism spectrum disorder, attention-deficit/hyperactivity disorder, and comorbid symptom presentation

Autism. 2021 Jan;25(1):227-243. doi: 10.1177/1362361320955107. Epub 2020 Sep 24.

Abstract

Many children with autism spectrum disorder (ASD) also have symptoms of attention-deficit hyperactivity disorder (ADHD). Children with ASD and ADHD often experience difficulties with inhibition. This study had the goal of understanding inhibition in children with ASD, ADHD, ASD + ADHD, and children who are typically developing (TD) using tasks that measured several aspects of inhibition. Results indicate that children with ASD + ADHD had greater difficulty inhibiting behavioral responses than TD children. Children with ASD + ADHD also differed from children with ASD and with ADHD in their inhibition of distracting information and strategic slowing of response speed. The four groups did not differ in their avoidance of potential losses. Children with ASD + ADHD exhibit a unique profile of inhibition challenges suggesting they may benefit from targeted intervention matched to their abilities.

Keywords: attention-deficit/hyperactivity disorder; autism spectrum disorder; cognition (attention, learning, memory); executive function; inhibition; interventions—psychosocial/behavioral; psychological theories of autism.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Attention Deficit Disorder with Hyperactivity* / epidemiology
  • Autism Spectrum Disorder*
  • Child
  • Developmental Disabilities
  • Executive Function
  • Humans
  • Inhibition, Psychological