Potential Issues With Virtual Populations When Applied to Nonlinear Quantitative Systems Pharmacology Models
CPT Pharmacometrics Syst Pharmacol
.
2020 Nov;9(11):613-616.
doi: 10.1002/psp4.12559.
Epub 2020 Sep 24.
Authors
Stephen Duffull
1
,
Abhishek Gulati
2
Affiliations
1
School of Pharmacy, University of Otago, Dunedin, New Zealand.
2
Clinical Pharmacology & Exploratory Development, Astellas Pharma Global Development Inc., Northbrook, Illinois, USA.
PMID:
32970387
PMCID:
PMC7679128
DOI:
10.1002/psp4.12559
No abstract available
MeSH terms
Biomarkers, Pharmacological / blood*
Computer Simulation
Drug Design
Humans
Nonlinear Dynamics
Pharmacology / methods*
Systems Biology / methods*
Substances
Biomarkers, Pharmacological