Functionalized Gold Nanoparticles: Synthesis, Properties and Biomedical Applications

Chem Rec. 2020 Dec;20(12):1474-1504. doi: 10.1002/tcr.202000087. Epub 2020 Sep 24.

Abstract

Gold nanoparticles have excellent optical and plasmon properties and have enormous research potential when they combine with different ligands. Functionalized gold nanoparticles are widely used in drug delivery, biological detection, sensors, and even clinical treatment. At present, with the rapid development of functionalized gold nanoparticles, we think it is necessary to sort out the recent research results. In this paper, the synthesis, characteristics, and biological applications of the three aspects are introduced. Firstly, the synthetic methods of functionalized gold nanoparticles are reviewed, and the improvement of the commonly used synthetic methods is summarized. Then, the catalytic properties, oxidation resistance, and chirality optical properties are summarized in detail. Finally, we summarize the research progress in the field of biology in recent years.

Keywords: Biomedical Applications; Functionalized Gold Nanoparticles; Synthesis; optical Properties.

Publication types

  • Review

MeSH terms

  • Gold / chemistry*
  • Microscopy, Electron, Transmission
  • Nanoparticles / chemistry*
  • Spectrophotometry, Ultraviolet
  • Surface Plasmon Resonance

Substances

  • Gold