COVID-19 in 17 Italian Pediatric Emergency Departments

Pediatrics. 2020 Dec;146(6):e20201235. doi: 10.1542/peds.2020-1235. Epub 2020 Sep 23.

Abstract

Background: Variability in presentation of children with coronavirus disease 2019 (COVID-19) is a challenge in emergency departments (EDs) in terms of early recognition, which has an effect on disease control and prevention. We describe a cohort of 170 children with COVID-19 and differences with the published cohorts.

Methods: Retrospective chart reviews on children (0-18 years) evaluated in 17 Italian pediatric EDs.

Results: In our cohort (median age of 45 months; interquartile range of 4 months-10.7 years), we found a high number of patients <1 year with COVID-19 disease. The exposure happened mainly (59%) outside family clusters; 22% had comorbidities. Children were more frequently asymptomatic (17%) or with mild diseases (63%). Common symptoms were cough (43%) and difficulty feeding (35%). Chest computed tomography, chest radiograph, and point-of-care lung ultrasound were used in 2%, 36%, and 8% of cases, respectively. Forty-three percent of patients were admitted because of their clinical conditions. The minimal use of computed tomography and chest radiograph may have led to a reduced identification of moderate cases, which may have been clinically classified as mild cases.

Conclusions: Italian children evaluated in the ED infrequently have notable disease symptoms. For pediatrics, COVID-19 may have rare but serious and life-threatening presentations but, in the majority of cases, represents an organizational burden for the ED. These data should not lower the attention to and preparedness for COVID-19 disease because children may represent a source of viral transmission. A clinically driven classification, instead of a radiologic, could be more valuable in predicting patient needs and better allocating resources.

Publication types

  • Multicenter Study

MeSH terms

  • Asymptomatic Infections / epidemiology
  • COVID-19 / diagnosis
  • COVID-19 / diagnostic imaging
  • COVID-19 / epidemiology*
  • COVID-19 Testing / statistics & numerical data
  • Child
  • Child, Preschool
  • Emergency Service, Hospital / statistics & numerical data*
  • Female
  • Humans
  • Infant
  • Italy / epidemiology
  • Male
  • Point-of-Care Testing / statistics & numerical data
  • Radiography, Thoracic / statistics & numerical data
  • Retrospective Studies
  • SARS-CoV-2*
  • Symptom Assessment
  • Systemic Inflammatory Response Syndrome / diagnosis
  • Systemic Inflammatory Response Syndrome / epidemiology
  • Tomography, X-Ray Computed / statistics & numerical data
  • Ultrasonography / statistics & numerical data

Supplementary concepts

  • pediatric multisystem inflammatory disease, COVID-19 related