Mesonephric Adenocarcinoma of the Uterine Fundus Exhibiting High 18F-FDG Uptake

Hyung Kyung Kim; Kyu Yeoun Won; Chanwoo Kim

doi:10.3390/diagnostics10090729

Mesonephric Adenocarcinoma of the Uterine Fundus Exhibiting High ¹⁸F-FDG Uptake

Diagnostics (Basel). 2020 Sep 21;10(9):729. doi: 10.3390/diagnostics10090729.

Authors

Hyung Kyung Kim¹, Kyu Yeoun Won¹, Chanwoo Kim²

Affiliations

¹ Department of Pathology, Kyung Hee University Hospital at Gangdong, Kyung Hee University School of Medicine, Seoul 05278, Korea.
² Department of Nuclear Medicine, Kyung Hee University Hospital at Gangdong, Kyung Hee University School of Medicine, Seoul 05278, Korea.

Abstract

Mesonephric adenocarcinoma is a rare tumor that is considered to develop from mesonephric remnants of the female genital tract. This tumor usually occurs in the lateral wall of the uterine cervix. Herein, we present an exceptionally rare case of mesonephric adenocarcinoma located in the uterine fundus. The tumor exhibited intense hypermetabolism on ¹⁸F-FDG PET/CT. Based on the characteristic histologic features and immunohistochemical phenotypes, the diagnosis of mesonephric adenocarcinoma was confirmed. The patient underwent hysterectomy with bilateral salpingo-oophorectomy and pelvic lymph node dissection, and no lymph node or distant metastasis was identified. After 20 months of surveillance without adjuvant therapy, she remains free of relapse.

Keywords: 18F-FDG PET/CT; mesonephric adenocarcinoma; uterine fundus.