Data on global analysis of clinical trials with probiotics

Theresia M G Dronkers; Arthur C Ouwehand; Ger T Rijkers

doi:10.1016/j.dib.2020.106269

Data on global analysis of clinical trials with probiotics

Data Brief. 2020 Sep 3:32:106269. doi: 10.1016/j.dib.2020.106269. eCollection 2020 Oct.

Authors

Theresia M G Dronkers¹, Arthur C Ouwehand², Ger T Rijkers^{1

3}

Affiliations

¹ Department of Sciences, University College Roosevelt, Lange Noordstraat 1, 4331 CB Middelburg, the Netherlands.
² DuPont Nutrition and Biosciences, Danisco Sweeteners Oy. Global Health and Nutrition Sciences, Sokeritehtaantie 20, Kantvik 02460, Finland.
³ Microvida Laboratory for Medical Microbiology and Immunology, St Elisabeth Hospital, Tilburg, the Netherlands.

Abstract

Data on characteristics of clinical trials with probiotics, registered at ClinicalTrials.gov were retrieved from the registry . Data on the registration process itself (moment of registration of the trial in relation to date of inclusion of first participant, data of completion of the study) as well as the number of participants were analysed. A trend analysis (over the period 2000-2020) was made of the number of participants in clinical trials with probiotics on gastrointestinal conditions and diseases. A comparison was made between conditions and diseases studied in completed clinical trials with those trials not yet recruiting participants. The data can be used and reused for assessment of the quality of clinical studies with probiotics and to identify future trends in applications of probiotics.

Keywords: Clinical trials; ClinicalTrials.gov; Probiotics; Registration.