Sea Cucumber Derived Type I Collagen: A Comprehensive Review

Mar Drugs. 2020 Sep 18;18(9):471. doi: 10.3390/md18090471.

Abstract

Collagen is the major fibrillar protein in most living organisms. Among the different types of collagen, type I collagen is the most abundant one in tissues of marine invertebrates. Due to the health-related risk factors and religious constraints, use of mammalian derived collagen has been limited. This triggers the search for alternative sources of collagen for both food and non-food applications. In this regard, numerous studies have been conducted on maximizing the utilization of seafood processing by-products and address the need for collagen. However, less attention has been given to marine invertebrates and their by-products. The present review has focused on identifying sea cucumber as a potential source of collagen and discusses the general scope of collagen extraction, isolation, characterization, and physicochemical properties along with opportunities and challenges for utilizing marine-derived collagen.

Keywords: applications; characterization; collagen; physicochemical properties; sea cucumber.

Publication types

  • Review

MeSH terms

  • Animals
  • Aquatic Organisms / metabolism*
  • Collagen Type I / chemistry*
  • Collagen Type I / isolation & purification
  • Humans
  • Sea Cucumbers / metabolism*

Substances

  • Collagen Type I