Off-the-shelf mesenchymal stem cells from human umbilical cord tissue can significantly improve symptoms in COVID-19 patients: An analysis of evidential relations

Phuc Van Pham; Ngoc Bich Vu

doi:10.4252/wjsc.v12.i8.721

Off-the-shelf mesenchymal stem cells from human umbilical cord tissue can significantly improve symptoms in COVID-19 patients: An analysis of evidential relations

World J Stem Cells. 2020 Aug 26;12(8):721-730. doi: 10.4252/wjsc.v12.i8.721.

Authors

Phuc Van Pham¹, Ngoc Bich Vu¹

Affiliation

¹ Stem Cell Institute, University of Science, Ho Chi Minh 08000, Viet Nam.

Abstract

Coronavirus disease-2019 (COVID-19) has affected more than 200 countries worldwide. This disease has hugely affected healthcare systems as well as the economy to an extent never seen before. To date, COVID-19 infection has led to about 165000 deaths in 150 countries. At present, there is no specific drug or efficient treatment for this disease. In this analysis based on evidential relationships of the biological characteristics of MSCs, especially umbilical cord (UC)-derived MSCs as well as the first clinical trial using MSCs for COVID-19 treatment, we discuss the use of UC-MSCs to improve the symptoms of COVID-19 in patients.

Keywords: COVID-19; Coronavirus; Mesenchymal stem cells; Umbilical cord-derived mesenchymal stem cells.

Publication types

Review