1 Whitehead Institute for Biomedical Research, Cambridge, MA, USA.
2 Whitehead Institute for Biomedical Research, Cambridge, MA, USA; Department of Biology, MIT, Cambridge, MA, USA. Electronic address: ajain@wi.mit.edu.
In this issue of Molecular Cell, Jalihal et al. (2020) show that cell volume changes upon osmotic stress result in rapid and reversible condensation of numerous multivalent proteins.