Pleural effusion. An unfamiliar presentation of ABPA

Monaldi Arch Chest Dis. 2020 Sep 9;90(4). doi: 10.4081/monaldi.2020.1380.

Abstract

Pleural effusion is rarely encountered in patients of allergic bronchopulmonary aspergillosis (ABPA). We report the case of a 17-year-old male who presented with complaints of fever, cough and increasing shortness of breath for 3 weeks. Patient had breathlessness with seasonal variation. Patient had right lower lobe consolidation with pleural effusion which did not respond to antibiotics. Pleural fluid was exudate with neutrophilic predominance and low ADA. Skin prick test for Aspergillus fumigatus was positive, both total IgE and specific IgE against Aspergillus fumigatus were raised.

Publication types

  • Case Reports

MeSH terms

  • Administration, Oral
  • Adolescent
  • Antifungal Agents / administration & dosage
  • Antifungal Agents / therapeutic use
  • Aspergillosis, Allergic Bronchopulmonary / complications*
  • Aspergillosis, Allergic Bronchopulmonary / drug therapy*
  • Aspergillosis, Allergic Bronchopulmonary / microbiology
  • Aspergillus fumigatus / immunology
  • Aspergillus fumigatus / isolation & purification
  • Cough / diagnosis
  • Drug Therapy, Combination
  • Dyspnea / diagnosis
  • Dyspnea / etiology
  • Eosinophils / immunology
  • Fever / diagnosis
  • Fever / etiology
  • Glucocorticoids / administration & dosage
  • Glucocorticoids / therapeutic use
  • Humans
  • Immunoglobulin E / immunology
  • Itraconazole / administration & dosage
  • Itraconazole / therapeutic use
  • Male
  • Neutrophils / immunology
  • Pleural Effusion / diagnostic imaging
  • Pleural Effusion / etiology*
  • Prednisolone / administration & dosage
  • Prednisolone / therapeutic use
  • Radiography, Thoracic / methods
  • Tomography, X-Ray Computed / methods
  • Treatment Outcome

Substances

  • Antifungal Agents
  • Glucocorticoids
  • Itraconazole
  • Immunoglobulin E
  • Prednisolone