Synthesis and Characterization of Graphene Oxide and Reduced Graphene Oxide Composites with Inorganic Nanoparticles for Biomedical Applications

Joanna Jagiełło; Adrian Chlanda; Magdalena Baran; Marcin Gwiazda; Ludwika Lipińska

doi:10.3390/nano10091846

Synthesis and Characterization of Graphene Oxide and Reduced Graphene Oxide Composites with Inorganic Nanoparticles for Biomedical Applications

Nanomaterials (Basel). 2020 Sep 15;10(9):1846. doi: 10.3390/nano10091846.

Authors

Joanna Jagiełło¹, Adrian Chlanda¹, Magdalena Baran¹, Marcin Gwiazda^{1

2}, Ludwika Lipińska¹

Affiliations

¹ Department of Chemical Synthesis and Flake Graphene, Łukasiewicz Research Network-Institute of Electronic Materials Technology, 133 Wólczyńska Str., 01-919 Warsaw, Poland.
² Faculty of Material Science and Engineering, Warsaw University of Technology, 141 Wołoska Str., 02-507 Warsaw, Poland.

Abstract

Graphene oxide (GO) and reduced graphene oxide (RGO), due to their large active surface areas, can serve as a platform for biological molecule adhesion (both organic and inorganic). In this work we described methods of preparing composites consisting of GO and RGO and inorganic nanoparticles of specified biological properties: nanoAg, nanoAu, nanoTiO₂ and nanoAg₂O. The idea of this work was to introduce effective methods of production of these composites that could be used for future biomedical applications such as antibiotics, tissue regeneration, anticancer therapy, or bioimaging. In order to characterize the pristine graphene materials and resulting composites, we used spectroscopic techniques: XPS and Raman, microscopic techniques: SEM with and AFM, followed by X-Ray diffraction. We obtained volumetric composites of flake graphene and Ag, Au, Ag₂O, and TiO₂ nanoparticles; moreover, Ag nanoparticles were obtained using three different approaches.

Keywords: biomaterials; composites; inorganic nanoparticles; reduced graphene oxide.

Abstract

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