Nanotechnology: Its Application in Treating Neurodegenerative Diseases

CNS Neurol Disord Drug Targets. 2021;20(1):34-53. doi: 10.2174/1871527319666200916121515.

Abstract

Neurodegenerative diseases such as Alzheimer's, Parkinson's and Huntington disease have serious concern due to its effect on the quality of life of affected persons. They have some limitations at diagnostic as well as the treatment level. Introducing nanotechnology, for the treatment of these diseases may contribute significantly to solve the problem. There are several treatment strategies for the neurodegenerative diseases, but most of them fail to cross the Blood-Brain Barrier (BBB). The present review highlights the application of nanotechnology during last the 20 years for the treatment of neurodegenerative diseases.

Keywords: Alzheimer's disease; Huntington's disease.; Nanotechnology; Parkinson's disease; nanoparticles; neurodegenerative disease.

Publication types

  • Review

MeSH terms

  • Blood-Brain Barrier
  • Humans
  • Nanoparticles
  • Nanotechnology / methods*
  • Neurodegenerative Diseases / drug therapy*
  • Quality of Life