New global dynamical results and application of several SVEIS epidemic models with temporary immunity

Appl Math Comput. 2021 Feb 1:390:125648. doi: 10.1016/j.amc.2020.125648. Epub 2020 Sep 10.

Abstract

This work applies a novel geometric criterion for global stability of nonlinear autonomous differential equations generalized by Lu and Lu (2017) to establish global threshold dynamics for several SVEIS epidemic models with temporary immunity, incorporating saturated incidence and nonmonotone incidence with psychological effect, and an SVEIS model with saturated incidence and partial temporary immunity. Incidentally, global stability for the SVEIS models with saturated incidence in Cai and Li (2009), Sahu and Dhar (2012) is completely solved. Furthermore, employing the DEDiscover simulation tool, the parameters in Sahu and Dhar'model are estimated with the 2009-2010 pandemic H1N1 case data in Hong Kong China, and it is validated that the vaccination programme indeed avoided subsequent potential outbreak waves of the pandemic. Finally, global sensitivity analysis reveals that multiple control measures should be utilized jointly to cut down the peak of the waves dramatically and delay the arrival of the second wave, thereinto timely vaccination is particularly effective.

Keywords: Global stability; Li-Muldowney geometric criterion; Nonlinear incidence; Parameter estimation; Temporary immunity; Vaccination.