Second-generation integrase strand inhibitors can be effective against elvitegravir-derived multiple integrase gene substitutions

AIDS. 2020 Nov 15;34(14):2155-2157. doi: 10.1097/QAD.0000000000002688.
No abstract available

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Drug Resistance, Viral*
  • HIV Infections / drug therapy
  • HIV Integrase / genetics*
  • HIV Integrase Inhibitors / pharmacology
  • HIV-1 / drug effects*
  • HIV-1 / genetics
  • Heterocyclic Compounds, 3-Ring / therapeutic use
  • Humans
  • Integrases / pharmacology*
  • Integrases / therapeutic use
  • Male
  • Pyridones / pharmacology
  • Quinolones / pharmacokinetics*
  • Quinolones / pharmacology
  • Raltegravir Potassium / pharmacology

Substances

  • HIV Integrase Inhibitors
  • Heterocyclic Compounds, 3-Ring
  • Pyridones
  • Quinolones
  • Raltegravir Potassium
  • elvitegravir
  • HIV Integrase
  • Integrases