Gonad dose assessment in paediatric kidney nuclear medicine test using Monte Carlo simulation

J Radiat Res. 2020 Nov 16;61(6):895-902. doi: 10.1093/jrr/rraa080.

Abstract

In this study, we evaluated the effect of radiation dose on gonads during paediatric kidney nuclear medicine tests. Using Monte Carlo simulations, the distribution and effects of radiation were physically evaluated by displaying the distribution path of the source in the human body over time. In particular, the evaluation of doses in children, who are sensitive to radiation during nuclear medicine tests that use internal exposure among several types of medical exposures, was conducted to obtain data for the management of medical exposures. Our results indicated that under normal kidney function, the dose received by the target kidney was 0.430 mGy/mCi, which is ~6% higher than the dose suggested by the International Commission on Radiation Protection (ICRP). Furthermore, when kidney function was compromised, the dose estimated was 0.726 mGy/mCi, which is ~2% lower than the dose suggested by the ICRP. In the male and female gonads, namely the testicles and ovaries, the doses received were 0.359 mGy/mCi and 0.394 mGy/mCi, respectively, under normal kidney function. Similarly, under abnormal kidney function, the doses ranged from 0.187 to 0.353 mGy/mCi and 0.238 to 0.388 mGy/mCi in the male and female gonads, respectively.

Keywords: Monte Carlo simulation; gonad dose assessment; kidney function; paediatric nuclear medicine test.

MeSH terms

  • Child
  • Computer Simulation
  • Female
  • Humans
  • Kidney / radiation effects*
  • Kidney Function Tests
  • Kinetics
  • Male
  • Monte Carlo Method
  • Nuclear Medicine / methods*
  • Ovary / radiation effects*
  • Radiation Dosage*
  • Radiometry / methods*
  • Testis / radiation effects*