Apoptosis signal-regulating kinase 1 (ASK1) as a therapeutic target for neurological diseases

Expert Opin Ther Targets. 2020 Nov;24(11):1061-1064. doi: 10.1080/14728222.2020.1821648. Epub 2020 Sep 30.

Authors

Satoshi Takenaka¹, Takao Fujisawa¹, Hidenori Ichijo¹

Affiliation

¹ The Laboratory of Cell Signaling, Graduate School of Pharmaceutical Sciences, The University of Tokyo , Tokyo, Japan.

PMID: 32930624
DOI: 10.1080/14728222.2020.1821648

No abstract available

Keywords: ASK1; Apoptosis signal-regulating kinase 1; amyotrophic lateral sclerosis; multiple sclerosis; neurological diseases.

Publication types

Editorial
Research Support, Non-U.S. Gov't

MeSH terms

Animals
Humans
MAP Kinase Kinase Kinase 5 / antagonists & inhibitors*
MAP Kinase Kinase Kinase 5 / metabolism
Molecular Targeted Therapy
Nervous System Diseases / drug therapy*
Nervous System Diseases / physiopathology

Substances

MAP Kinase Kinase Kinase 5
MAP3K5 protein, human