Infliximab-related weight gain in inflammatory bowel disease: associations and financial impacts

Intern Med J. 2020 Sep;50(9):1134-1138. doi: 10.1111/imj.14987.

Abstract

Association between tumour necrosis alpha inhibitors and weight gain has been reported. We examined weight change in our cohort of inflammatory bowel disease patients treated with infliximab (IFX) for over 12 months, its associations and financial implications. Two-thirds of patients gained weight during the course of therapy. The mean change in weight after 12 months of IFX therapy was 3.3 (±6.5) kg.

MeSH terms

  • Cohort Studies
  • Humans
  • Inflammatory Bowel Diseases* / chemically induced
  • Inflammatory Bowel Diseases* / drug therapy
  • Infliximab / adverse effects
  • Tumor Necrosis Factor-alpha*
  • Weight Gain

Substances

  • Tumor Necrosis Factor-alpha
  • Infliximab