Synthesis of Pharmacological Relevant 1,2,3-Triazole and Its Analogues-A Review

Abstract

In this review, authors focus mostly on the various synthetic strategies developed so far for 1,2,3- triazole scaffold and its derivatives via different approaches such as metal-free, metal assisted or bimetallic. A brief overview of applications of the very important 1,2,3-triazole scaffold along with pharmacological activity is also discussed. Synthetic strategies are updated until June 2020.

Keywords: 1; 2; 3-triazoles; applications; click chemistry; pharmacologically active compounds; scaffold; synthesis.