Solar UV Exposure and Mortality from Skin Tumors: An Update

Adv Exp Med Biol. 2020:1268:143-154. doi: 10.1007/978-3-030-46227-7_7.

Abstract

Solar UV exposure is critical and complex in the etiology and prognosis of skin cancer, particularly cutaneous malignant melanoma. Sun exposure and one of its "derivatives," vitamin D, have been implicated in protection against mortality from melanoma. However, the relationships are inconsistent. At this time, it is not possible to make clear recommendations for or against sun exposure in relationship to melanoma prognosis. However, this relationship deserves continued exploration.

Keywords: Cutaneous melanoma; Mortality; Nonmelanoma skin cancer; UV exposure; Vitamin D.

Publication types

  • Review

MeSH terms

  • Humans
  • Melanoma / etiology
  • Melanoma / mortality
  • Melanoma / prevention & control
  • Neoplasms, Radiation-Induced / etiology
  • Neoplasms, Radiation-Induced / mortality
  • Neoplasms, Radiation-Induced / prevention & control
  • Prognosis
  • Skin Neoplasms / etiology
  • Skin Neoplasms / mortality*
  • Skin Neoplasms / prevention & control
  • Ultraviolet Rays* / adverse effects
  • Vitamin D

Substances

  • Vitamin D