Utilization of Endovascular and Surgical Treatments for Symptomatic Uterine Leiomyomas: A Population Health Perspective

J Vasc Interv Radiol. 2020 Oct;31(10):1552-1559.e1. doi: 10.1016/j.jvir.2020.04.039. Epub 2020 Sep 9.

Abstract

Purpose: To conduct a population-level analysis of surgical and endovascular interventions for symptomatic uterine leiomyomata by using administrative data from outpatient medical encounters.

Materials and methods: By using administrative data from all outpatient hospital encounters in California (2005-2011) and Florida (2005-2014), all patients in the outpatient setting with symptomatic uterine leiomyomata were identified. Patients were categorized as undergoing hysterectomy, myomectomy, uterine artery embolization (UAE), or no intervention. Hospital stay durations and costs were recorded for each encounter.

Results: A total of 227,489 patients with uterine leiomyomata were included, among whom 39.9% (n = 90,800) underwent an intervention, including hysterectomy (73%), myomectomy (19%), or UAE (8%). The proportion of patients undergoing hysterectomy increased over time (2005, hysterectomy, 53.2%; myomectomy, 26.9%; UAE, 18.0%; vs 2013, hysterectomy, 80.1%; myomectomy, 14.4%; UAE, 4.0%). Hysterectomy was eventually performed in 3.5% of patients who underwent UAE and 4.1% who underwent myomectomy. Mean length of stay following hysterectomy was significantly longer (0.5 d) vs myomectomy (0.2 d) and UAE (0.3 d; P < .001 for both). The mean encounter cost for UAE ($3,772) was significantly less than those for hysterectomy ($5,409; P < .001) and myomectomy ($6,318; P < .001). Of the 7,189 patients who underwent UAE during the study period, 3.5% underwent subsequent hysterectomy.

Conclusions: The proportion of women treated with hysterectomy in the outpatient setting has increased since 2005. As a lower-cost alternative with a low rate of conversion to hysterectomy, UAE may be an underutilized treatment option for patients with uterine leiomyomata.

Publication types

  • Multicenter Study

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • California
  • Cost Savings
  • Cost-Benefit Analysis
  • Databases, Factual
  • Endovascular Procedures / adverse effects
  • Endovascular Procedures / economics
  • Endovascular Procedures / trends*
  • Female
  • Florida
  • Hospital Costs / trends
  • Humans
  • Hysterectomy / adverse effects
  • Hysterectomy / economics
  • Hysterectomy / trends*
  • Leiomyoma / economics
  • Leiomyoma / therapy*
  • Length of Stay
  • Middle Aged
  • Population Health
  • Postoperative Complications / etiology
  • Practice Patterns, Physicians' / economics
  • Practice Patterns, Physicians' / trends*
  • Retrospective Studies
  • Time Factors
  • Treatment Outcome
  • Uterine Artery Embolization / adverse effects
  • Uterine Artery Embolization / economics
  • Uterine Artery Embolization / trends*
  • Uterine Myomectomy / adverse effects
  • Uterine Myomectomy / economics
  • Uterine Myomectomy / trends*
  • Uterine Neoplasms / economics
  • Uterine Neoplasms / therapy*
  • Young Adult