An Update on Screening and Prevention for Breast and Gynecological Cancers in Average and High Risk Individuals

Am J Med Sci. 2020 Nov;360(5):489-510. doi: 10.1016/j.amjms.2020.06.008. Epub 2020 Jun 10.

Abstract

Breast and gynecological cancers affect almost 900,000 women and therefore most health care providers will be involved at some point in the management of women with cancer. As the prognosis of all cancers is much more favorable when diagnosed in early stages, it is imperative that all health care providers are familiar not only with current screening guidelines for the average population, but also with the identification of high risk individuals who may benefit from more intense screening as well as available interventions to prevent disease or decrease risk. The purpose of this review article is to provide relevant information to physicians and other health care providers to aid in identifying patients that are classified as "high risk" for developing breast or a gynecologic cancer, outlining what interventions exist for adequate screening and risk reduction strategies, and to provide an update on current screening guidelines for individuals at average and high risk.

Keywords: Breast Cancer; Cancer Screening; Cervical Cancer; HPV Vaccination; Ovarian Cancer; Prevention; Risk Reduction.

Publication types

  • Review

MeSH terms

  • Breast Neoplasms / diagnosis*
  • Breast Neoplasms / genetics
  • Breast Neoplasms / prevention & control*
  • Early Detection of Cancer / methods
  • Female
  • Genetic Predisposition to Disease / genetics
  • Genetic Predisposition to Disease / prevention & control
  • Hormone Replacement Therapy / adverse effects
  • Humans
  • Ovarian Neoplasms / diagnosis*
  • Ovarian Neoplasms / prevention & control*
  • Risk Factors
  • Smoking / adverse effects
  • Smoking / genetics
  • Uterine Cervical Neoplasms / diagnosis*
  • Uterine Cervical Neoplasms / genetics
  • Uterine Cervical Neoplasms / prevention & control*