The Language Development Via FOXP2 in Autism Spectrum Disorder: A Review

Curr Pharm Des. 2020;26(37):4789-4795. doi: 10.2174/1381612826666200909141108.

Abstract

Background: An increasing number of newborn children in numerous nations are enrolled in early childhood education programs, and instructors, in this way, assume a focal job in invigorating language improvement in these youthful kids. Kids with language issues are found to have a higher risk for future scholarly challenges and learning inabilities. Language advancement among kids is an intricate procedure and vital for correspondence. The shortcomings in the utilization of grammatical structures may lessen the useful utilization of language for verbally expressive kids with autism spectrum disorder and exacerbate troubles with academic and social expertise advancement.

Results: FOXP2, the single principal gene connected to a speech and language issue, is significant for the right execution of complex motor behaviors used for speech. In any case, changes in FOXP2 lead to a speech/language issue portrayed by childhood apraxia of speech. These days, language learning is fundamentally required for kids who need to move to different nations to pursue the instructive frameworks and be helpful individuals or residents of those nations.

Conclusion: The purpose of this study was to explore the role of FOXP2 in language disorder and its management for children's language and communication development.

Keywords: FOXP2; autism; children; disease; language; teacher.

Publication types

  • Review

MeSH terms

  • Autism Spectrum Disorder*
  • Child
  • Child, Preschool
  • Forkhead Transcription Factors / genetics
  • Humans
  • Infant, Newborn
  • Language Development
  • Language Disorders*

Substances

  • FOXP2 protein, human
  • Forkhead Transcription Factors