Snatching the Crown from SARS-CoV-2

Lynda Coughlan

doi:10.1016/j.chom.2020.08.007

Snatching the Crown from SARS-CoV-2

Cell Host Microbe. 2020 Sep 9;28(3):360-363. doi: 10.1016/j.chom.2020.08.007.

Author

Lynda Coughlan¹

Affiliation

¹ Icahn School of Medicine at Mount Sinai, Department of Microbiology, New York, NY 10029, USA; University of Maryland Baltimore School of Medicine, Department of Microbiology and Immunology and Center for Vaccine Development and Global Health, Baltimore, MD 21201, USA. Electronic address: lcoughlan@som.umaryland.edu.

Abstract

In this issue of Cell Host & Microbe, three papers describe the pseudotyping of vesicular stomatitis virus (VSV) with the SARS-CoV-2 spike. This VSV-CoV-2-S platform allows virus neutralization assays to be performed at BSL-2 and also has applications as a candidate vectored vaccine to elicit protective immunity against SARS-CoV-2.

Publication types

Comment

MeSH terms

Antibodies, Neutralizing*
Betacoronavirus
COVID-19
Coronavirus Infections*
Humans
Pandemics*
Peptidyl-Dipeptidase A
Pneumonia, Viral*
SARS-CoV-2

Substances

Antibodies, Neutralizing
Peptidyl-Dipeptidase A

Abstract

Publication types

MeSH terms

Substances

Grants and funding