Management of CNS toxicity of chemotherapy and targeted agents: 2020

Am J Cancer Res. 2020 Aug 1;10(8):2617-2620. eCollection 2020.

Abstract

Cancer treatment has evolved significantly over the last two decades. With the advent of targeted therapy, immunotherapy and immunotherapeutic agents conjugated to toxins, the spectrum of side effects has increased. This work is a compilation of side effects on the central nervous system due to various chemotherapeutic and immunotherapy agents followed by their recommended management.

Keywords: Intrathecal (IT); central nervous system (CNS); posterior reversible encephalopathy syndrome (PRES).