Purpose: To compare the in vitro optical performance of five premium multifocal intraocular lenses (IOLs), including a single-valued metric that shows the total range of distances where a multifocal IOL generates an acceptable image quality.
Methods: Through-focus modulation transfer function (MTF) and the image of a United States Air Force target were obtained for a 3-mm pupil and a wavelength of 546 nm in five multifocal IOLs (Tecnis Symfony [Johnson & Johnson], FineVision Micro F [PhysIOL], Acrysof IQ PanOptix [Novartis], and Artis Symbiose Mid and Plus [Cristalens Industrie] multifocal IOLs). Total depth of focus (TDOF) is computed by adding the vergence intervals where the through-focus MTF at 50 cycles/mm is 0.15 or greater.
Results: Due to their different optical designs (bifocal, trifocal, or extended depth of focus), energy is distributed differently between far, intermediate, and near focus for each multifocal IOL. The light distribution of the Symbiose Mid and Plus multifocal IOLs was similar, concentrating the energy into far focus and the intermediate into near focus, but extending the intermediate focus more (Plus) or less (Mid) toward the near focus. TDOFs were: 1.58 diopters [D] (FineVision); 1.71 D (Tecnis Symfony); 1.73 D (Artis Symbiose Plus); 1.74 D (Artis Symbiose Mid); and 1.90 D (Acrysof IQ PanOptix).
Conclusions: TDOFs were similar between multifocal IOLs with a maximum difference of 0.32 D and mean value of 1.73 D. The combination of the Symbiose Mid and Plus IOLs can theoretically provide a TDOF of 2.90 D in case one is implanted in one eye and the other in the fellow eye. [J Refract Surg. 2020;36(9):578-584.].
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