A Review on the Serum Electrolytes and Trace Elements Role in the Pathophysiology of COVID-19

Biol Trace Elem Res. 2021 Jul;199(7):2475-2481. doi: 10.1007/s12011-020-02377-4. Epub 2020 Sep 8.

Abstract

All the world is involved in the COVID-19 disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Coronavirus is a positive-sense RNA and has an envelope. There is no specific drug for this disease and treatment methods are limited. Malnutrition and electrolyte imbalance can make dysfunction in the immune system and impairment of the immune system causes increasing the risk of infection. Understanding the aspects of biological features of the virus will help the development of diagnostic tests, pharmacological therapies, and vaccines. Here, we review and discuss increasing and decreasing some trace elements and imbalance of serum and plasma electrolytes involving in COVID-19.

Keywords: Covid-19; Electrolytes; Micronutrients; Trace elements.

Publication types

  • Review

MeSH terms

  • COVID-19*
  • Diagnostic Tests, Routine
  • Electrolytes
  • Humans
  • SARS-CoV-2
  • Trace Elements*

Substances

  • Electrolytes
  • Trace Elements