Genomic Screening for Malignant Hyperthermia Susceptibility

Anesthesiology. 2020 Dec 1;133(6):1277-1282. doi: 10.1097/ALN.0000000000003547.

Abstract

It is timely to consider the utility and practicability of screening for malignant hyperthermia susceptibility using genomic testing. Here the authors pose a simple, but bold question: what would it take to end deaths from malignant hyperthermia? The authors review recent advances and propose a scientific and clinical pathway toward this audacious goal to provoke discussion in the field.

Publication types

  • Research Support, N.I.H., Extramural
  • Review

MeSH terms

  • Genetic Predisposition to Disease / genetics*
  • Genetic Testing / methods*
  • Genomics / methods
  • Humans
  • Malignant Hyperthermia / diagnosis*
  • Malignant Hyperthermia / genetics*