Immune Checkpoint Inhibitor Therapy Induces Inflammatory Activity in Large Arteries

Circulation. 2020 Dec 15;142(24):2396-2398. doi: 10.1161/CIRCULATIONAHA.120.048708. Epub 2020 Sep 8.
No abstract available

Keywords: FDG; atherosclerosis; immune checkpoint inhibitor therapy; inflammation; positron emission tomography.

Publication types

  • Letter

MeSH terms

  • Aged
  • Aged, 80 and over
  • Aorta / diagnostic imaging
  • Aorta / drug effects*
  • Aorta / immunology
  • Arteritis / chemically induced*
  • Arteritis / diagnostic imaging
  • Arteritis / immunology
  • CTLA-4 Antigen / antagonists & inhibitors
  • Female
  • Fluorodeoxyglucose F18
  • Humans
  • Iliac Artery / diagnostic imaging
  • Iliac Artery / drug effects*
  • Iliac Artery / immunology
  • Immune Checkpoint Inhibitors / adverse effects*
  • Immunity, Innate / drug effects
  • Male
  • Melanoma / drug therapy*
  • Melanoma / immunology
  • Melanoma / pathology
  • Middle Aged
  • Neoplasm Staging
  • Positron Emission Tomography Computed Tomography
  • Programmed Cell Death 1 Receptor / antagonists & inhibitors
  • Radiopharmaceuticals
  • Retrospective Studies
  • Risk Factors
  • Skin Neoplasms / drug therapy*
  • Skin Neoplasms / immunology
  • Skin Neoplasms / pathology

Substances

  • CTLA-4 Antigen
  • CTLA4 protein, human
  • Immune Checkpoint Inhibitors
  • PDCD1 protein, human
  • Programmed Cell Death 1 Receptor
  • Radiopharmaceuticals
  • Fluorodeoxyglucose F18