Enhancing the prediction of childhood asthma remission: Integrating clinical factors with microRNAs

J Allergy Clin Immunol. 2021 Mar;147(3):1093-1095.e1. doi: 10.1016/j.jaci.2020.08.019. Epub 2020 Sep 2.

Abstract

The novel integration of baseline clinical and microRNA variables significantly improves the long-term individualized prediction of childhood asthma remission by early adulthood compared to using clinical variables alone.

Publication types

  • Letter
  • Randomized Controlled Trial
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Anti-Inflammatory Agents / therapeutic use*
  • Asthma / diagnosis*
  • Asthma / drug therapy
  • Asthma / genetics
  • Cytokines / metabolism
  • Double-Blind Method
  • Female
  • Humans
  • Inflammation Mediators / metabolism
  • Male
  • MicroRNAs / genetics
  • Placebo Effect
  • Prognosis
  • Th2 Cells / immunology*
  • Treatment Outcome
  • Young Adult

Substances

  • Anti-Inflammatory Agents
  • Cytokines
  • Inflammation Mediators
  • MIRN221 microRNA, human
  • MicroRNAs