Data on identification of primary and secondary metabolites in aqueous extract of Verbascum betonicifolium

Maria Luísa Serralheiro; Rita Guedes; Sezan R Fadel; Hamdi Bendif

doi:10.1016/j.dib.2020.106146

Data on identification of primary and secondary metabolites in aqueous extract of Verbascum betonicifolium

Data Brief. 2020 Aug 6:32:106146. doi: 10.1016/j.dib.2020.106146. eCollection 2020 Oct.

Authors

Maria Luísa Serralheiro^{1

2}, Rita Guedes¹, Sezan R Fadel³, Hamdi Bendif^{4

5}

Affiliations

¹ BioISI - Biosystems & Integrative Sciences Institute, University of Lisbon, Faculty of Sciences, Lisboa, Campo Grande, 1749-016 Lisboa, Portugal.
² Department of Chemistry and Biochemistry, University of Lisbon, Faculty of Science, Campo Grande, 1749-016 Lisboa, Portugal.
³ Technical University of Dresden, Bergstrasse 66, 01069 Dresden, Germany.
⁴ Natural and Life Sciences Department, Faculty of Sciences, University of M'sila, 28000 Msila, Algeria.
⁵ Laboratoire d'Ethnobotanique et des Substances Naturelles, Département des Sciences Naturelles, Ecole Normale Supérieure (ENS), Kouba, 16308 Alger, Algeria.

Abstract

Tentative identification of primary and secondary metabolites in aqueous extracts from aerial parts of Verbascum betonicifolium Kuntze was done. This plant belongs to the Scrophulariaceae family and is used for several treatments in folk medicine. One of the processes commonly used to prepare this plant for consumption is boiling with water during approximately 20 minutes, that is, a decoction process. After filtration, this decoction was analysed in search for bioactive metabolites. The analysis was carried out by Electro-Spray Ionization (ESI) and High-Resolution Mass Spectrometry (HRMS) was done using a Quadropole Time-of-Flight (QToF, Impact II, Bruker), coupled to an Ultra High-Performance Liquid Chromatography (UHPLC, ELUTE autosampler, Bruker). The analysis was done in the negative mode (ESI-) and the identification was accomplished using the molecular formula suggestions from the Data Analysis 4.4™ software from Bruker and some databases, like Metlin and PubChem, always confirming with MS/MS results. These data can be used for finding biomarkers between Verbascum sps or to complementary medicine practitioners to get a scientific based knowledge of their results. These data are the unpublished supplementary materials related to "Bioactivities of Iridoids and flavonoids present in decoctions from aerial parts of Verbascum betonicifolium" (Fadel et al., 2020, submitted).

Keywords: Glycosidic derivatives; HRMS; Phenolic compounds; Phytochemical composition; Secondary metabolite; Terpenoids; Verbascum betonicifolium.