Objectives: To compare the features of patients with peptic ulcer between Han and Uyghur ethnicity from 2013 to 2018 in Xinjiang and to provide the evidence of prevention and treatment for the different ethnicity.
Methods: Data of 3 586 patients with peptic ulcer (3 293 Han and 293 Uyghur) in the Karamay Central Hospital of Xinjiang, including the detection rate of peptic ulcer, helicobacter pylori (Hp) detection rate of population, season, gender, lesion location and complication, were collected from January 2013 to December 2018 and compared between 2 nationalities.
Results: There were significant difference in the detection rate of peptic ulcer and population's Hp between Han and Uyghur (P<0.01). The detection rates for peptic ulcer of Han were sustainable declined from 15.20% to 10.23%, while Uyghur's detective rates for peptic ulcer were raised again from 17.49% to 8.38%. The Hp detection rate of Uyghur's population was higher than that of Han (P<0.01). There were significant difference in the season's detection rate for peptic ulcer between Han and Uyghur (P<0.01). The detection rate for peptic ulcer of Han was the highest in the winter, while that of Uyghur was the highest in the spring. The detective rate of Uyghur's peptic ulcer was significant higher than that of Han in the spring (P<0.01). The detection rates for peptic ulcer of 2 nationality were the highest at ≤25 age groups, the detection rate for Uyghur's peptic ulcer was higher than that of Han at ≤35 age groups (P<0.05). There were more men than women in peptic ulcer in the 2 nationalities. The approximate proportion was 2꞉1. The rates of multiple gastric ulcer and compound duodenal ulcer of Han were more than those of Uyghur (P<0.05), but the rate for pyloric obstruction of Uyghur patient was higher than that of Han (P<0.05).
Conclusions: There are statistical difference in detection rate of PU, Hp detection rate of population, morbidity season, age, complication and the rate of complex ulcer between Han and Uyghur, However, there aren't statistical difference in Hp detection rate of peptic ulcer patient, the gender, lesion location between the 2 nationalities during last 6 years.
目的: 分析新疆汉族和维吾尔族2013―2018年消化性溃疡(peptic ulcer，PU)检出率、人群幽门螺杆菌(helicobacter pylori，Hp)检出率、发病季节、患者年龄和性别、溃疡部位和并发症等疾病特征，研究两民族PU发病趋势和特点，为不同民族PU防治工作侧重提供依据。方法: 收集2013年1月到2018年12月两民族在新疆克拉玛依市中心医院就诊确诊为PU的患者共3 586例，其中汉族3 293例、维吾尔族293例，比较两民族PU检出率、人群Hp检出率、发病季节、患者年龄和性别、溃疡部位和并发症等疾病特征。结果: 两民族PU检出率差异有统计学意义(P<0.01)，汉族近年来PU检出率呈下降趋势，由15.20%降至10.23%，而维吾尔族PU检出率从17.49%降至最低时8.38%，又升至17.16%。维吾尔族人群Hp检出率高于汉族(P<0.01)。两民族PU四季检出率差异有统计学意义(P<0.01)，汉族PU检出率最高的季节为冬季，而维吾尔族则为春季，春季维吾尔族PU(主要是十二指肠溃疡)检出率明显高于汉族(P<0.01)。两民族PU检出率均在≤25岁年龄段最高，维吾尔族≤35岁年龄段PU检出率高于汉族(P<0.05)。两民族PU患者中男性人数均多于女性人数，比例约为2꞉1。汉族多发胃溃疡检出率、十二指肠溃疡复合溃疡率比维吾尔族高(P<0.05)，但维吾尔族幽门梗阻检出率比汉族高，差异有统计学意义(P<0.05)。结论: 2013―2018年两民族PU检出率、人群Hp检出率、发病季节、患者年龄、复合溃疡率、并发症等存在差异，而PU患者Hp检出率、性别、病变部位等无差异。.
Keywords: Han people; Uyghur people; duodenal ulcer; gastric ulcer; peptic ulcer.